ABSTRACT
Rheumatic fever remains a significant health problem in Jordan. We retrospectively reviewed medical charts of 28 boys and 22 girls [mean age at presentation 10.5 +/- 2.6 years] with confirmed diagnosis based on modified Jones criteria at Queen Alia Heart Institute from February 1999 to February 2002. Arthritis was the commonest major manifestation [88%; 68% migratory], carditis was second commonest [48%; 8% silent carditis] and chorea was seen in 6%. None had subcutaneous nodules or erythema marginatum. The mitral valve was most commonly affected [80%]; both mitral and aortic valves were affected in 25%. Pericarditis was seen in 12.5% and acute congestive heart failure in 4%. Practitioners should be aware of diverse clinical presentations and emphasize strict adherence to prophylaxis guidelines
Subject(s)
Adolescent , Child , Female , Humans , Male , Acute Disease , Age Distribution , Anti-Bacterial Agents , Child Welfare , Echocardiography, Doppler , Erythema/etiology , Guideline Adherence , Heart Failure/etiology , Pericarditis/etiology , Practice Guidelines as Topic , Public Health , Sensitivity and Specificity , Sex DistributionABSTRACT
We studied the correlation of fibrinogen and plasma lipids in a 9 month old Jordanian girl with afibrinogenaemic proposita. The study design was a pedigree analysis composed of three generations, and 31 individuals. Age, gender, plasma fibrinogen, total cholesterol, triglycerides, LDL-cholesterol were measured. Our proposita plasma fibrinogen was absent, in addition to hyperlipidaemia type IIa. Her father's phenotype was IIb, and mother's was type IV. The family phenotypes were consistent with familial combined hyperlipidaemia